Triglyceride Down-regulates Expression of MSR-1 in PMA-induced THP-1 Macrophages
نویسندگان
چکیده
منابع مشابه
Brucella melitensis and Mycobacterium tuberculosis depict overlapping gene expression patterns induced in infected THP-1 macrophages
Pathogens infecting mammalian cells have developed various strategies to suppress and evade their hosts’ defensive mechanisms. In this line, the intracellular bacteria that are able to survive and propagate within their host cells must have developed strategies to avert their host’s killing attitude. Studying the interface of host-pathogen confrontation can provide valuable information for defi...
متن کاملbrucella melitensis and mycobacterium tuberculosis depict overlapping gene expression patterns induced in infected thp-1 macrophages
pathogens infecting mammalian cells have developed various strategies to suppress and evade their hosts’ defensive mechanisms. in this line, the intracellular bacteria that are able to survive and propagate within their host cells must have developed strategies to avert their host’s killing attitude. studying the interface of host-pathogen confrontation can provide valuable information for defi...
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BACKGROUND Periodontitis is a chronic inflammatory disease induced by periodontopathogens such as Porphyromonas gingivalis (P. gingivalis). MicroRNAs (miRNAs) are small single-stranded noncoding RNAs that regulate gene expression at the level of translation. MiRNAs have been reported to be involved in inflammatory processes. In this study, we examined the effects of P. gingivalis-induced inflam...
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Silymarin is a hepatoprotective mixture of flavonolignans and flavonoids extracted from the seeds of milk thistle (Silybum marianum L. Gaertn). This study investigates the effect of major bioactive constituents from silymarin, silybin A, silybin B, isosilybin A, isosilybin B, silydianin, silychristin, isosilychristin, and taxifolin, on the expression of ABCA1, an important cholesterol efflux tr...
متن کاملEnginEEring and natural SciEncES Triglyceride Regulation of Lysosomal Cholesterol in THP-1 Macrophages
The central question I investigated in my research this semester was how the cholesterol and triglyceride metabolic pathways interact in macrophages when cholesterol levels are high. What factors prevent or enhance macrophage ability to regulate cholesterol metabolism? We have preliminary evidence that excessive cholesterol accumulation in macrophages alters triglyceride metabolism in these cel...
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ژورنال
عنوان ژورنال: Biomedical Science Letters
سال: 2020
ISSN: 2288-7415
DOI: 10.15616/bsl.2020.26.3.164